Unique Identifier
94194946
Authors
Lai ZF. Hotokebuchi N. Cragoe EJ Jr. Nishi K.
Institution
Department of Pharmacology, Kumamoto University School of Medicine, Japan.
Title
Effects of 5-(N,N-hexamethylene)amiloride on action potentials, intracellular Na, and pH of guinea pig ventricular muscle in vitro.
Source
Journal of Cardiovascular Pharmacology. 23(2):259-67, 1994 Feb.
NLM Journal Code
k78
Country of Publication
United States
MeSH Subject Headings

Acidosis / ci [Chemically Induced]
Acidosis / pp [Physiopathology]
Action Potentials / de [Drug Effects]
*Amiloride / aa [Analogs & Derivatives]
Amiloride / pd [Pharmacology]
Ammonium Chloride / pd [Pharmacology]
Animal
Female
Guinea Pigs
*Heart / de [Drug Effects]
Heart Ventricle / de [Drug Effects]
Heart Ventricle / me [Metabolism]
Hydrogen-Ion Concentration
In Vitro
Ion-Selective Electrodes
Kinetics
Male
Microelectrodes
*Myocardium / me [Metabolism]
Papillary Muscles / de [Drug Effects]
*Sodium / me [Metabolism]
Support, Non-U.S. Gov't

Abstract
Registry Numbers
12125-02-9 (Ammonium Chloride). 1428-95-1 (5-(N,N-hexamethylene)amiloride). 2609-46-3 (Amiloride). 7440-23-5 (Sodium).
ISSN
0160-2446
Publication Type
Journal Article.
Language
English
Entry Month
9407. 1